Canadian Pediatric Neuromuscular Group
Completed Clinical Trials
ACE- 031 Acceleron Pharma, Inc.
Study of ACE-031 in Subjects With Duchenne Muscular Dystrophy
Canadian Sites:
1) Alberta Children's Hospital - Calgary, AB
2) BC Chidlren's Hospital - Vancouver, BC
3) McMaster Children's Hospital - Hamilton, ON
4) Children's Hospital -London Health Sciences Centre - London, ON
5) Children's Hospital of Eastern Ottawa - Ottawa, ON
For more information visit the clinical trials website below:
https://clinicaltrials.gov/ct2/show/study/NCT01099761?term=ace-031+dmd&rank=1
ACE-031 Acceleron Pharma Inc.
Extension Study of ACE-031 in Subjects With Duchenne Muscular Dystrophy
Canadian sites:
1) Alberta Children's Hospital - Calgary, AB
2) McMaster Children's Hospital - Hamilton, ON
3) Children's Hospital -London Health Sciences Centre - London, ON
4) Children's Hospital of Eastern Ottawa - Ottawa, ON
For more information visit the clinical trials website below:
https://clinicaltrials.gov/ct2/show/study/NCT01239758?term=ace-031+dmd&rank=2
Drisapersen - GlaxoSmithKline - Completed
A Clinical Study to Assess the Efficacy and Safety of GSK2402968 in Subjects With Duchenne Muscular Dystrophy (DMD114044)
Canadian Sites:
1) BC Children's Hospital - Vancouver, BC
2) Children's Hospital - London Health Sciences Centre - London, ON
3) CHU Ste- Justine - Montreal, QC
For more information visit the clinical trials website below:
https://clinicaltrials.gov/ct2/show/study/NCT01254019?term=dmd114044&rank=1&show_locs=Y#locn
Drisapersen - GlaxoSmithKline - Completed
Open Label Study of GSK2402968 in Subjects With Duchenne Muscular Dystrophy
Canadian Sites:
1) BC Children's Hospital - Vancouver, BC
2) Children's Hospital - London Health Sciences Centre - London, ON
3) CHU Ste- Justine - Montreal, QC
For more information visit the clinical trials website below:
https://clinicaltrials.gov/ct2/show/study/NCT01480245?term=GSK+drisapersen&rank=3&show_locs=Y#locn
Drisapersen - BioMarin- Completed
A Study of the Safety, Tolerability & Efficacy of Long-term Administration of Drisapersen in US & Canadian Subjects
Candian Sites
1) BC Children's Hospital - Vancouver, BC
2) Children's Hospital- London Health Sciences Centre - London, ON
3) Hôpital Ste. Justine - Montreal, QC
For more information visit the clinical trials website below:
https://clinicaltrials.gov/ct2/show/NCT01803412?term=biomarin+dmd&rank=4
PF-06252616 - Pfizer - Completed
An Open-label Extension Study To Evaluate Safety Of PF-06252616 In Boys With Duchenne Muscular Dystrophy
Candian Sites
1) Alberta Children's Hospital- Calgary, AB
2) BC Children's Hospital - Vancouver, BC
3) Children's Hospital- London Health Sciences Centre - London, ON
4) Hôpital Ste. Justine - Montreal, QC
For more information visit the clinical trials website below:
https://clinicaltrials.gov/ct2/show/study/NCT02907619?cond=dmd&cntry=CA&show_locs=Y
PF-06252616 - Pfizer - Completed
A Phase 2 Randomized, Double-Blind, Placebo‑Controlled, Multiple Ascending Dose Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of PF-06252616 in Ambulatory Boys with Duchenne Muscular Dystrophy
Candian Sites
1) Alberta Children's Hospital- Calgary, AB
2) BC Children's Hospital - Vancouver, BC
3) Children's Hospital- London Health Sciences Centre - London, ON
4) Hôpital Ste. Justine - Montreal, QC
For more information visit the clinical trials website below:
https://clinicaltrials.gov/ct2/show/NCT02310763?term=PF-06252616&rank=2
SMNRx- ISIS - Completed
A Phase 3, Randomized, Double-blind, Sham-Procedure Controlled Study to Assess the Clinical Efficacy and Safety of ISIS 396443 Administered Intrathecally in Patients With Later-onset Spinal Muscular Atrophy
Canadian sites
1) Children's Hospital- London Health Sciences Centre - London, ON
2) The Research Institute of the McGill University Health Centre
- Montreal, QC
For more information and participant eligibility visit the clinical trial site below:
https://clinicaltrials.gov/ct2/show/NCT02292537?term=SMA+ISIS&rank=5
SMNRx- ISIS - Completed
A Phase 3, Randomized, Double-blind, Sham-Procedure Controlled Study to Assess the Clinical Efficacy and Safety of ISIS 396443 Administered Intrathecally in Patients With Infantile-onset Spinal Muscular Atrophy
Canadian sites:
1) Hospital for Sick Children - Toronto, ON
2) The Research Institut of the McGill University Health Centre
- Montreal, QC
3) British Columbia's Children's Hospital- Vancouver, BC
For more information and participant eligibility visit the clinical trial site below:
https://clinicaltrials.gov/ct2/show/study/NCT02193074?term=SMA+ISIS&rank=4&show_locs=Y#locn